17/12/2024 - Press release
Phase 1/2 of the clinical trial shows that the administration of the AEF0217 molecule developed by the biotech Aelis Farma, is safe and can improve key skills such as communication, social interactions and daily living for people with Down syndrome These results reinforce the start of the phase 2 clinical trial, through an international multicenter study with people with Down syndrome, focused on the dose necessary to achieve the treatment goal
11/12/2024 - Press release
Consuming 20-30% of daily energy intake in the morning influences key cardiovascular risk factors. People who consume the right amount of energy in the morning have 2-3.5% lower body mass index, less abdominal obesity (2-4% smaller waist circumference), 9-18% lower triglycerides, and 4-8.5% higher HDL cholesterol (the good cholesterol). Additionally, having a high-quality breakfast with a balanced intake of proteins, high-value fats, fiber, calcium, and iron is associated with a 1.5% smaller waist circumference, 4% lower triglycerides, and 3% higher HDL cholesterol. The study tracked nearly 400 participants of the PREDIMED-Plus study over three years, which analyzes the effects of the Mediterranean diet on participants' health.
Més informació "Having a good breakfast reduces cardiovascular risk"
02/12/2024 - Press release
A study by the Hospital del Mar Research Institute, in collaboration with the University of Vic-Central University of Catalonia (UVic-UCC), published in the Revista Española de Cardiología, validates the effectiveness of this type of initiative. Implementing out-of-hospital care programs reduces the fatality rate of heart attacks by 35% and long-term mortality by 27%.
19/11/2024 - Press release
A scientific article by the PASOS consortium, led by the Gasol Foundation and the Hospital del Mar Research Institute, confirms that nearly 60% of children with overweight present abdominal obesity. 56.1% of the population aged 8 to 16 with overweight (based on BMI) has an excess of fat around the waist, a percentage that 20 years ago stood at 40%. Abdominal obesity is associated with visceral fat, a condition defining cardiometabolic risk, which already affects more than 1 million children aged 8 to 16 in Spain. The PASOS study by the Gasol Foundation continues to contribute to scientific evidence and understanding the issue of childhood obesity.
18/11/2024 - Press release
The p95HER2 protein is found expressed in one third of HER2+ tumors, which represent 4% of all tumors. Led by VHIO investigators, CAR T cells targeting p95HER2 have been engineered to secrete the TECH2Me bispecific antibody. Both therapies specifically and independently recognize tumor cells. In addition, the TECH2Me bispecific antibody activates immune cells within the tumor microenvironment. This dual mechanism of action has demonstrated safety and achieved complete and durable antitumor responses in patient-derived models of HER2+ p95HER2-expressing solid tumors. Published in Nature Communications, results of this VHIO-led study have provided the rationale for the application of a phase 1 first-in-human clinical trial, currently in the approval process, to assess this novel therapeutic strategy in patients with HER2-driven solid tumors.
13/11/2024 - Press release
Conversely, women tolerate it better than men, according to a multicenter study led by Hospital del Mar and its research institute, published in the Journal of Cardiothoracic and Vascular Anesthesia. The study analyzed the outcomes of more than 200 people who underwent a thoracotomy, a type of open surgery that requires separating the ribs to reach the lungs. The differences between men and women are not due to physiological or genetic factors but to a worse initial situation for women regarding their quality of life prior to surgery. The researchers highlight the need to consider this and introduce the idea of addressing psychological components before surgery as part of a personalized approach to pain management.
Més informació "They demonstrate that women suffer more chronic postoperative pain than men"
12/11/2024 - Press release
Dr. Monllau is Professor of Traumatology and Orthopedic Surgery, and Dr. Castells has held the Chair of Preventive Medicine and Public Health since September 12. Both at the Department of Medicine and Health Sciences of the UPF. Dr. Joan Carles Monllau, head of the Orthopedic Surgery and Traumatology Service of the Hospital del Mar and researcher of the Group in cellular research in inflammation and cartilage of the Hospital del Mar Research Institute. Dr. Castells is head of service emeritus of the Epidemiology and Evaluation Service of the Hospital del Mar and investigator of the Epidemiology and Evaluation Research Group of the Hospital del Mar Research Institute.
08/11/2024 - Press release
This project is a study on the characterization of genomic complexity in patients with chronic lymphocytic leukemia treated with targeted therapies. Joanna Kamaso, a predoctoral researcher at the Hospital del Mar Research Institute, has received one of the 10 grants awarded by the Fundación Española de Hematología y Hemoterapia (FEHH) for research projects at state institutions. The grant award ceremony took place during the 66th Congress of the Sociedad Española de Hematología y Hemoterapia , held in Palma de Mallorca from October 26 to 28.
06/11/2024 - Press release
This study will be conducted in collaboration with the Josep Carreras Leukemia Research Institute, and researchers from Finland, the Netherlands, and the United Kingdom will participate. The goal is to develop and validate protocols and systems for generating laboratory-derived stem cells to regenerate patients' blood. The European Research Council, which provides these grants, is the leading funding organization for advanced and excellent research on the continent. It is an organization created by the European Union.
29/10/2024 - Press release
They have received three of the 61 grants awarded by SEOM as part of its annual congress held in Madrid. The Sociedad Española de Oncología Médica has awarded 61 grants to medical oncologists, three of them to professionals from Hospital del Mar and its research institute. This is the highest number of grants in its history, with a total allocation of nearly 1.3 million euros. The awards were presented at the society's congress, held from October 15 to 18 in Madrid.
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