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• 07/07/2010 - General information

  Kidney disease in patients with heart-related chest pain increases the mortality risk

  According to an international study which IMIM took part, kidney disease is a significant predictor of in-hospital mortality and 30-day mortality in patients who come to the hospital with heart-related chest pain, otherwise known as Non-ST-segment Elevation Acute Coronary Syndrome (NSTE-ACS).

  Més informació "Kidney disease in patients with heart-related chest pain increases the mortality risk"

• 02/06/2010 - Press release

  Comparison of the human genome with genomes of other animals helps to identify new functional repetitive structures in proteins

  A project executed by the research group on Evolutionary Genomics of GRIB (IMIM -UPF) employed comparison of the human genome with the genomes of other species of vertebrates to verify that the repetitive motifs found in human proteins are important for the good operation of the body and which could correspond to the fraction of the genome called ‘junk’ (with no function).

  Més informació "Comparison of the human genome with genomes of other animals helps to identify new functional repetitive structures in proteins"

• 28/05/2010 - General information

  Commercial release of Pentacle, an advanced tool for 3D QSAR and Virtual screening developed at GRIB

  Molecular Discovery Ltd, one of the world leader companies in chemoinformatics and services for the pharmaceutical industry has launched to the market the software Pentacle, developed at the Computer of Assisted Drug Design (CADD) laboratory by Ángel Durán and Manuel Pastor.

  Més informació "Commercial release of Pentacle, an advanced tool for 3D QSAR and Virtual screening developed at GRIB"

• 16/04/2010 - Events

  The chronic lymphocytic leukaemia project reveals the first oncogenic mutations

  The International Cancer Genome Consortium, which will study the genomes of more than 25,000 cancer patients, has presented its latest research results in the journal Nature. The chronic lymphocytic leukemia genome project is coordinated in Spain, and the researcher Nuria López-Bigas, head of Biomedical Genomics laboratory of GRIB (IMIM-UPF) participates on the bioinformatics analysis of data and the coordination and management of Consortium data.

  Més informació "The chronic lymphocytic leukaemia project reveals the first oncogenic mutations"

• 26/04/2010 - Press release

  The ARITMO Project Researches the Risk of Arrhythmia that May Be Caused by Some Antipsychotic, Antihistamine and Anti-Infective Drugs

  

  Cardiac arrhythmia caused by medications is a priority in pharmacological safety as they are difficult to predict. Sudden cardiac death and Torsades de Pointes (TDP) are serious side effects of some antipsychotic, antihistamine and anti-infective drugs that induce prolonged QT intervals.

  Més informació "The ARITMO Project Researches the Risk of Arrhythmia that May Be Caused by Some Antipsychotic, Antihistamine and Anti-Infective Drugs"

• 15/04/2010 - General information

  A work published in Genome Research identifies many new functional amino acid tandem repeats in human proteins

  

  The Evolutionary Genomics group of GRIB (IMIM- UPF), led by Mar Albà, has published at the journal Genome Research a study that shows, using a comparative genomics approach, that many more amino acid tandem repeats in human proteins than previously suspected are likely to be functional.

  Més informació "A work published in Genome Research identifies many new functional amino acid tandem repeats in human proteins"

• 02/03/2010 - Press release

  Polyphenols, fundamental to regulating genes involved in heart disease

  

  A study carried out by researchers at the Municipal Institute of Medical Research (IMIM-Hospital del Mar) has shown for the first time that the beneficial effects of virgin olive oil, a rich source of polyphenols in the Mediterranean diet, can cause changes in the manifestation of certain genes involved in atherosclerosis.

  Més informació "Polyphenols, fundamental to regulating genes involved in heart disease"

• 01/03/2010 - General information

  iPHACE, Software to Visually Explore Pharmacological Space

  

  On 15 February, the international journal Bioinformatics, one of the best in the field of mathematics and computational biology, published an article on a web application developed by the Laboratorio de Quimiogenómica, directed by Jordi Mestres, which is part of the IMIM-UPF Biomedicine IT Research Group (GRIB).

  Més informació "iPHACE, Software to Visually Explore Pharmacological Space"

• 25/02/2010 - General information

  José Antonio Pascual re-elected as President of the IPC Anti-doping Committee

  

  José Antonio Pascual, member of the Bioanalysis and Analytical Services Research Group of the Neuropsychopharmacology Programme and deputy director of the Anti-doping Control Laboratory, has been re-elected President of the International Paralympic Committee’s Anti-doping Committee for the next 4 years.

  Més informació "José Antonio Pascual re-elected as President of the IPC Anti-doping Committee"

• 23/02/2010 - General information

  25 European organisations unite their efforts towards a better prediction of toxic effects of new drug candidates

  

  The Innovative Medicines Initiative (IMI) funds for 5 years a consortium consisting of 13 European pharmaceutical companies and 12 academic groups and SMEs to develop information technologies-based solutions for improved toxicity prediction of new drug candidates. The academic coordination of the project is in charge of Ferran Sanz, Director of GRIB (IMIM-UPF).

  Més informació "25 European organisations unite their efforts towards a better prediction of toxic effects of new drug candidates"