Clinical and Molecular Epidemiology of Cancer

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Epidemiology and Public Health Programme

Group Leader

Miquel Porta Serra

We conduct integrative scientific research on human pancreatic cancer at all causal and mechanistic levels, from genomics to clinical medicine to the social and physical environment. Our aim is to achieve an optimal integration of professional cultures, scientific knowledge, methodologies and techniques from epidemiology and public health, clinical medicine and the biological sciences. We are a team that has worked across disciplines for more than three decades, one of the pioneer groups in Europe on clinical and molecular epidemiology. Cancer is a complex set of processes that result from the accumulation of genetic, epigenetic and other alterations during the lifecourse. Thus, integrative studies on the causes of cancer are a natural meeting point between molecular biology and epidemiology. We are also a world-recognized research group on the biomonitoring of internal body concentrations of environmental chemical agents (‘internal contamination’) in representative samples of the general population.

Research group

Members

Immaculada Collet Diví (Technician)

Magda Gasull Panadès (Technician)

José Antonio Pumarega Rodríguez (Technician)

Yolanda Rovira Pons (Research Assistant)

Main PublicationsOngoing Research ProjectsParticipation in Research NetworksThesesAppointmentsOutreach

Main Publications

• Camargo J, Pumarega J, Alguacil J, Sanz-Gallén P, Gasull M, Delclos GL, Amaral AF, Porta M. Toenail concentrations of trace elements and occupational history in pancreatic cancer. Environ Int 2019; 127: 216-225. IF 7.943. Q1.

• Gasull M, Pumarega J, Kiviranta H, Rantakokko P, Raaschou-Nielsen O, Bergdahl IA, et al. Methodological issues in a prospective study on plasma concentrations of persistent organic pollutants and pancreatic cancer risk within the EPIC cohort. Environ Res 2019; 169: 417-433. IF 5.026. Q1.

• Porta M, Vandenberg LN. There are good clinical, scientific, and social reasons to strengthen links between biomedical and environmental research. J Clin Epidemiol 2019; 111: 124-126. IF 4.65. Q1.

• Llorente C, Revuelta G, Carrió M, Porta M. Scientists' opinions and attitudes towards citizens' understanding of science and their role in public engagement activities. PLoS One 2019; 14(11): e0224262. IF 2.776. Q2.

• Gómez-Tomás Á, Pumarega J, Alguacil J, Amaral AFS, Malats N, Pallarès N, Gasull M, Porta M; PANKRAS II Study Group. Concentrations of trace elements and KRAS mutations in pancreatic ductal adenocarcinoma. Environ Mol Mutagen 2019; 60(8): 693-703. IF 2.528. Q2.

See all Publications

Ongoing Research Projects

• Influencia de las concentraciones de compuestos tóxicos persistentes sobre la mortalidad, la incidencia de trastornos crónicos y la expresión de miARN en población general

- Financing institution: Fondo de Investigación Sanitaria. ISCIII (PI17/00088)

- Period: from 2017 to 2020