Internal Services

Consulting Service on Methodology for Research

The objective of the Consulting Service on Methodology for Biomedical Research (AMIB) is to offer support on methodology and statistics applied to biomedical research to investigators of Parc de Salut Mar and health care centers and IMIM.

The services offered are:

• Consultation regarding protocol design

• Sample size estimation

• Creation of randomization lists

• Design, management and quality control of data bases

• Statistical analysis

• Report writing

• Consulting on presentations and publications

Publications

• Aguirrezabal A, Ferrer M, Marco E, Mojal S, Vilagut G, Duarte E. Evaluación de la satisfacción con el programa de rehabilitación tras el ictus: validación de la versión española de la Pound Satisfaction Scale. Med Clin (Barc) 2016; 147(10): 441-443. IF 1.267. Q2.

• Anguiano L, Riera M, Pascual J, Valdivielso JM, Barrios C, Betriu A, Clotet S, Mojal S, Fernández E, Soler MJ, investigators from the NEFRONA study. Circulating angiotensin converting enzyme 2 activity as a biomarker of silent atherosclerosis in patients with chronic kidney disease. Atherosclerosis 2016; 253: 135-143. IF 3.942. Q1.

• Bermejo S, Soler MJ, Gimeno J, Barrios C, Rodríguez-García E, Mojal S, Pascual J. Factores predictivos de nefropatía no diabética en pacientes diabéticos. Utilidad de la biopsia renal. Nefrología 2016; 36(5): 535-544. IF 1.207. Q4.

• Chalela R, González-García JG, Chillarón JJ, Valera-Hernández L, Montoya-Rangel C, Badenes D, Mojal S, Gea J. Impact of hyponatremia on mortality and morbidity in patients with COPD exacerbations. Respir Med 2016; 117: 237-242. IF 3.036. Q2.

• Curto-Barredo L, Yélamos J, Gimeno R, Mojal S, Pujol RM, Giménez-Arnau AM. Basophil Activation Test identifies the patients with Chronic Spontaneous Urticaria suffering the most active disease. Immun Inflamm Dis 2016; 4: 441-445.

• Fondevilla E, Grau S, Mojal S, Palomar M, Matas L, Gudiol F, on behalf of the VINCat Group. Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013. Expert Rev Anti Infect Ther 2016; 14(1): 137-144. IF 3.542. Q1.

• Salman-Monte TC, Torrente V, Almirall M, Corzo P, Mojal S, Carbonell J. Prevalence and predictors of vitamin D insufficiency in supplemented and non-supplemented women with systemic lupus erythematosus in the Mediterranean region. Rheumatol Int 2016; 36(7): 975-985. IF 1.702. Q3.

• Sánchez-Rodríguez MD, Marco E, Ronquillo-Moreno N, Miralles R, Mojal S, Vázquez-Ibar O, Escalada F, Muniesa JM. The PSSMAR study. Postacute sarcopenia: Supplementation with B-hydroxyMethylbutyrate after resistance training: Study protocol of a randomized, double-blind controlled trial. Maturitas 2016; 94: 117-124. IF 3.12. Q1.

• Sans-Atxer L, Pascual J, Radosevic A, Quintian C, Ble M, Molina L, Mojal S, Ballarin JA, Torra R, Fernández-Llama P. Renal volume and cardiovascular risk assessment in normotensive autosomal dominant polycystic kidney disease patients. Medicine 2016; 95(49): e5595. IF 1.206. Q3.

• Vallecillo G, Mojal S, Roquer A, Samos P, Luque S, Martínez-Sanvisens D, Martires PK, Torrens M. Low Non-structured Antiretroviral Therapy Interruptions in HIV-Infected Persons Who Inject Drugs Receiving Multidisciplinary Comprehensive HIV Care at an Outpatient Drug Abuse Treatment Center. AIDS Behav 2016; 20(5): 1068-1075. IF 3.063. Q1.

Freezers and Cryopreservation

This service is dedicated to the maintenance and supervision of the centralized -20°C and -80°C large freezers area as well as the liquid nitrogen area.

Services

• Monitoring of the process of supplyingliquid nitrogen to the tanks

• Monitoring of the process of refilling the nitrogen tanks

• Process of supplying liquid nitrogen to portable containers

• Monitoring of proper freezer operation with a system of alarms connected to the IMIM Maintenance Service

• Assignment of space in the -80ºC freezers and LN2 containers

• Temperature control of all refrigeration units and issuing of reports

• Storage and distribution of dry ice

• Technical support and scientific consultancy and advisement

Equipment

• 56 freezers of -80ºC ultra-low temperature

• 4 temperature-controlled rooms (Temp and O2 control in one room)

• 3 chambers of -20ºC

• 4 chambers of 4ºC

• 3 combined refrigerator/freezers (double sensor)

• 5 freezers of -20ºC

All the equipment has sensors to monitor the different parameters of the units.

Every week, the temperature records are sent to the different research groups that use the equipment. In 2016, a total of 9 new requests for cryopreservation space were processed.

Cell Culture Service

Preparation of culture media

There is a service for users to prepare cell culture media for them on demand.

In 2016, a total of 253 applications for the mycoplasma test were received and a total of 1.140 culture media were prepared under request.

Cell line maintenance service

The bank has more than 140 tumor and normal cell lines, kept frozen in liquid nitrogen.

The service includes maintenance of the bank of cell lines, replacement of stocks and distribution of frozen vials to users under request.

Requests to the cell line bank in 2016:

Communications to congresses

The action to improve the characterization of cell lines bank led to the presentation of a poster communication at the VII National Congress of Biobanks / I Latin American Congress of Biobanks, Santiago de Compostela, November 2016: Arregui L, Mayol X, Garcia C, Navarro P, Alayo I, Torà M. Cell lines bank: Cryopreservation effect on cell viability along the time.

Funding

2016: Contract research support/FIS-12. Fondo de Investigación Sanitaria. ISCII (4111008263)

Sterilization and Cleaning

The Sterilization and Cleaning Service provides support for the research laboratories in keeping the facilities clean (lab tables, fume-cupboard glass, cabinets), as well as taking care of fungible material.

The service carries out daily sterilization controls and all records and reports are filed for examination.

C/ Doctor Aiguader, 88

08003 Barcelona

(+34) 93 316 04 00

info@imim.es