Girona Heart Registry

Research group

< Epidemiology and Public Health Programme

Group Leader

Jaume Marrugat de la Iglesia

The mission of the Girona Heart Registry Research Group is to increase our knowledge of the magnitude of the populational problem of cardiovascular diseases, their molecular, cellular and environmental mechanisms, and design the best strategies for preventing them.

The ultimate goal of this knowledge is to significantly reduce the burden of this disease on society, creating tools –such as cardiovascular risk functions– that allow us to transfer the knowledge we acquire to clinical practice.

The REGICOR Group also has the mission of training new researchers in this area of knowledge.

Members

Irene Roman Degano (Researcher)

Susanna Tello Rovira (Technician)

Silvia Pérez Fernández (Technician)

Joan Salvador Vila Domènech (Technician)

Gemma Blanchart Cuella (Technician)

Sandra Farré Anton (Research Assistant)

Yolanda Ferrer Campo (Research Assistant)

Sònia Gaixas Vasallo (Research Assistant)

Main Publications

• Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, (... Marrugat J ...), et al. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet 2018; 50(10): 1412-1425. IF 27.125. D1.

• Ramos R, Comas-Cufí M, Martí-Lluch R, Balló E, Ponjoan A, Alves-Cabratosa L, Blanch J, Marrugat J, Elosua R, Grau M, Elosua-Bayés M, García-Ortiz L, Garcia-Gil M. Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study. BMJ 2018; 362: k3359. IF 23.259. D1.

• Baena-Díez JM, Subirana I, Ramos R, Gómez de la Cámara A, Elosua R, Vila JS, Marín-Ibáñez A, Guembe MJ, Rigo F, Tormo-Díaz MJ, Moreno-Iribas C, Cabré JJ, Segura A, Lapetra J, Quesada M, Medrano MJ, González-Diego P, Frontera G, Gavrila D, Ardanaz E, Basora J, García JM, García-Lareo M, Gutiérrez-Fuentes JA, Mayoral E, Sala J, Degano IR, Francés A, Castell C, Grau M, Marrugat J*. Evaluación de la validez de las funciones SCORE de bajo riesgo y calibrada para población española en las cohortes FRESCO. Rev Esp Cardiol 2018; 71(4): 274-282.

• Elosua-Bayés M, Martí-Lluch R, García-Gil MM, Camós L, Comas-Cufí M, Blanch J, Ponjoan A, Alves-Cabratosa L, Elosua R, Grau M, Marrugat J, Ramos R. Asociación de los factores de riesgo cardiovascular y estilos de vida clásicos con el índice vascular corazón-tobillo en población general mediterránea. Rev Esp Cardiol 2018; 71(6): 458-465. IF 5.166. Q1.

• Vázquez-Oliva G, Zamora A, Ramos R, Martí R, Subirana I, Grau M, Degano IR, Marrugat J, Elosua R. Tasas de incidencia y mortalidad, y letalidad poblacional a 28 días del infarto agudo de miocardio en adultos mayores. Estudio REGICOR. Rev Esp Cardiol 2018; 71(9): 718-725. IF 5.166. Q1.

• Vázquez-Oliva G, Zamora A, Ramos R, Subirana I, Grau M, Degano IR, Muñoz D, Fitó M, Elosua R, Marrugat J. Valor predictivo de la albúmina plasmática, la vitamina D y las apolipoproteínas A y B como biomarcadores de riesgo coronario en el estudio REGICOR. Rev Esp Cardiol 2018; 71(11): 910-916. IF 5.166. Q1.

• Subirana I, Fitó M, Díaz O, Vila JS, Francés A, Delpon E, Sanchis J, Elosua R, Muñoz D, Degano IR, Marrugat J. Prediction of coronary disease incidence by biomarkers of inflammation, oxidation, and metabolism. Sci Rep 2018; 8(1): 3191. IF 4.122. Q1.

• Barroso M, Goday A, Ramos R, Marín-Ibañez A, Guembe MJ, Rigo F, Tormo-Díaz MJ, Moreno-Iribas C, Cabré JJ, Segura A (...), Grau M, Marrugat J, FRESCO Investigators. Interaction between cardiovascular risk factors and body mass index and 10-year incidence of cardiovascular disease, cancer death, and overall mortality. Prev Med 2018; 107: 81-89. IF 3.483. Q1.

Ongoing Research Projects

• Trastorns afectius i risc cardiovascular en població general: efecte diferencial dels mecanismes fisiopatològics

- Financing institution: Departament de Salut, Generalitat de Catalunya (SLT006/17/00234)

- Period: from 2018 to 2020