Addiction

Research group

Group Leader

Marta Torrens Melich

This is a multidisciplinary team of health professionals (psychiatrists, psychologists, internist, nurses…) that share clinical, research and teaching activities. In the research area, the main aim is to study addiction to substances from different perspectives to improve secondary prevention and treatment. Main lines of research are: 1) clinical and therapeutic aspects of substance use disorders (opiates, cocaine, alcohol, cannabis…); 2) Psychiatric and somatic (i.e. HIV, HCV) comorbidity in substance use disorders (diagnostic tools, neurobiology, factors associated, treatment…); 3) New psychoactive substances of abuse (detection of abuse, potential neurotoxicity) and 4) Gender perspective of Addictions

2017

Members

Mònica Astals Vizacino (Researcher)

Claudio Guillermo Castillo Buenaventura (Researcher)

Maria Francina Fonseca Casals (Researcher)

Juan Ignacio Mestre Pintó (Researcher)

Álvaro José Palma Conesa (Researcher)

María Robles Martínez (Researcher)

Judit Tirado Muñoz (Researcher)

Gabriel Vallecillo Sánchez (Researcher)

Gerard Mateu Codina (PhD Student)

María Alías Ferri (Technician)

Adriana Farré Martínez (Technician)

Alexandra Garcia Guix (Technician)

Raúl Guijarro Palma (Technician)

Lluís Mangot Sala (Technician)

Gloria Marín Alba (Technician)

María Rosario Valera Fernández (Technician)

Group’s Recognitions

Main Publications

• Blanco-Hinojo L, Pujol J, Harrison BJ, Macià D, Batalla A, Nogué S, Torrens M, Farré M, Deus J, Martín-Santos R. Attenuated frontal and sensory inputs to the basal ganglia in cannabis users. Addict Biol 2017; 22(4): 1036-1047. IF 4.603. D1.

• García-Marchena N, Pavón FJ, Pastor A, Araos P, Pedraz M, Romero-Sanchiz P, Calado M, Suárez J, Castilla-Ortega E, Orio L, Boronat A, Torrens M, Rubio G, de la Torre R, Rodríguez-de Fonseca F, Serrano A. Plasma concentrations of oleoylethanolamide and other acylethanolamides are altered in alcohol-dependent patients: effect of length of abstinence. Addict Biol 2017; 22(5): 1366-1377. IF 4.603. D1.

• Dematteis M, Auriacombe M, D'Agnone O, Somaini L, Szerman N, Littlewood R, Alam F, Alho H, Benyamina A, Bobes J, Daulouede JP, Leonardi C, Maremmani I, Torrens M, Walcher S, Soyka M. Recommendations for buprenorphine and methadone therapy in opioid use disorder: a European consensus. Expert Opin Pharmacother 2017; 18(18): 1987-1999. IF 3.894. Q1.

• García-Marchena N, Araos PF, Barrios V, Sánchez-Marín L, Chowen JA, Pedraz M, Castilla-Ortega E, Romero-Sanchiz P, Ponce G, Gavito AL, Decara J, Silva D, Torrens M, Argente J, Rubio G, Serrano A, Rodríguez-de Fonseca F, Pavón FJ. Plasma Chemokines in Patients with Alcohol Use Disorders: Association of CCL11 (Eotaxin-1) with Psychiatric Comorbidity. Front Psychiatry 2017; 7: 214. IF 3.532. Q1.

• Keller B, Mestre J, Álvaro-Bartolomé M, Martínez-Sanvisens D, Farré M, García-Fuster MJ, García-Sevilla JA, Torrens M. A Biomarker to Differentiate between Primary and Cocaine-Induced Major Depression in Cocaine Use Disorder: The Role of Platelet IRAS/Nischarin (I1-Imidazoline Receptor). Front Psychiatry 2017; 8: 258. IF 3.532. Q1.

• Grebely J, Bruneau J, Lazarus JV, Dalgard O, Bruggmann P, Treloar C, Hickman M, Hellard M, Roberts T, Crooks L, Midgard H, Larney S, Degenhardt L, Alho H, Byrne J, Dillon JF, Feld JJ, Foster G, Goldberg D, Lloyd AR, Reimer J, Robaeys G, Torrens M, Wright N, Maremmani I, Norton BL, Litwin AH, Dore GJ, on behalf of the International Network on Hepatitis in Substance Users. Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs. Int J Drug Policy 2017; 47: 51-60. IF 3.479. Q1.

• Quintana P, Ventura-Vilamala M, Grifell M, Palma A, Galindo L, Fornís I, Gil-Lladanosa C, Carbón X, Caudevilla F, Farré M, Torrens M. The hidden web and the fentanyl problem: Detection of ocfentanil as an adulterant in heroin. Int J Drug Policy 2017; 40: 78-83. IF 3.479. Q1.

• Gutiérrez-Sacristán A, Bravo A, Portero M, Valverde O, Armario A, Blanco-Gandía MC, Farré A, Fernández-Ibarrondo L, Fonseca F, Giraldo J, Leis A, Mané A, Mayer MA, Montagud S, Nadal R, Ortiz J, Pavón FJ, Pérez EJ, Rodríguez-Arias M, Serrano A, Torrens M, Warnault V, Sanz F, Furlong LI. Text mining and expert curation to develop a database on psychiatric diseases and their genes. Database (Oxford) 2017; 2017: bax043. IF 3.29. Q1.

• Gilchrist G, Swan D, Widyaratna K, Márquez-Arrico JE, Hughes E, Mdege ND, Martyn-St James M, Tirado-Muñoz J. A Systematic Review and Meta-analysis of Psychosocial Interventions to Reduce Drug and Sexual Blood Borne Virus Risk Behaviours Among People Who Inject Drugs. AIDS Behav 2017; 21(7): 1791-1811. IF 2.916. D1.

Ongoing Research Projects

• Adaptación de los instrumentos de diagnóstico de patología dual a los criterios DSM-5

- Fondo de Investigación Sanitaria. ISCIII (PI14/00178)

- From 2015 to 2019

- Principal investigator: Mestre Pintó, Juan Ignacio

• Biomarcadores de la Depresión Inducida: BIODEP

- Fondo de Investigación Sanitaria. ISCIII (PI16/00603)

- From 2017 to 2019

- Principal investigator: Torrens Melich, Marta; Fonseca Casals, Francina

• Biomarcadores de consumo de alcohol: evaluación adultos y menores

- Ministerio de Sanidad y Política Social (2013I062)

- From 2014 to 2017

- Principal investigador: Fonseca Casals, Maria Francina

• Bases neurobiológicas de la depresión inducida por sustancias de abuso: NEURODEP-2

- Fondo de Investigación Sanitaria. ISCIII (PI12/01838)

- From 2013 to 2017